How to Take PIQRAY

PIQRAY® (alpelisib) tablets + fulvestrant

Q&A for taking PIQRAY

PIQRAY tablets is a once-daily oral tablet that is prescribed with fulvestrant. Fulvestrant is an injectable hormone therapy administered by your health care provider. It is important to always follow your doctor's directions on how to take PIQRAY.

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How should I take PIQRAY?Take PIQRAY exactly as your health care provider tells you. Take it once a day at about the same time, with food.

Can I change my dose of PIQRAY?Do not change your dose or stop taking PIQRAY unless your health care provider tells you.

What if I miss my dose of PIQRAY? If you miss a dose of PIQRAY, you may still take it with food up to 9 hours after the time you usually take it. If it has been over 9 hours after you usually take your dose:

  • Skip the dose for that day.
  • Take the dose at your usual time the next day.
  • Do not take 2 doses to make up for a missed dose time.
  • If you vomit after taking PIQRAY, do not take another dose that day. Take your next dose at your usual time.

Can I chew or crush my PIQRAY tablets?Swallow PIQRAY tablets whole. Do not chew, crush, or split them. Do not take any tablets that are broken, cracked, or that look damaged.

What if I take too much PIQRAY?If you take too much PIQRAY, call your health care provider or go to the nearest hospital emergency room right away.

Get to know treatment with PIQRAY

When starting a new treatment, you may have questions and concerns. This onboarding video can provide some important, useful information to help you better understand treatment with PIQRAY. If you have any further questions, talk to your doctor.

Learn about the recommended dosing schedule

The recommended dose of PIQRAY is 300 mg (two 150-mg film-coated tablets) taken orally, once daily, with food. When given with PIQRAY, the recommended dose of fulvestrant is 500 mg administered as an injection by your doctor on days 1, 15, and 29, and once monthly thereafter. Ask your doctor for additional dosing information for fulvestrant.

PIQRAY® (alpelisib) + fulvestrant dosing schedule

Find out more about PIQRAY packaging

The PIQRAY blister pack is designed to help you stay on track with treatment. The pack is color-coded to help you take the right dose on the right day.

PIQRAY blister pack
PIQRAY blister pack
PIQRAY blister pack